83% of the pesticide exposed people were found to have autoantibodies in their blood, in comparison to only 15% for non-pesticide exposed control group. Pro-inflammatory IL-6 (interleukin-6) was also significantly elevated in farmers compared to controls. The findings add to a growing body of evidence that exposure to chemicals such as pesticides may at least contribute to the brain damage seen in Parkinson's. However, cleft palate did occur in 2% of animals exposed to 20 mg/kg of CPZ, 20% of animals exposed to 50 mg/kg of CPZ and 91% of animals exposed to the highest 100 mg/kg dose. Healthy children had no mesureable levels of the pesticide lindane, View Original Journal Summary Along with the doubling of ADHD for children testing positive for the pesticide, every 10-fold increase in 3-PBA resulted in an additional 50% increase in hyperactive-impulsive behavior. The same trend was also seen with hydrocephalus - 0% for the animals not exposed to CPZ, 6% for animals exposed to 20 mg/kg, 19% for animals exposed to 50 mg/kg, 32% for animals exposed to 75 mg/kg and 100% for the 12 animals exposed to the 100 mg/kg level. Results were compared to a control group of 30 individuals without a history of pesticide exposure. Immediately following each patient's exposure to the pesticide, common complaints included an initial flu-like illness followed by chronic complaints of fatigue, headaches, dizziness, loss of memory, upper and lower respiratory symptoms, joint and muscle pain and gastrointestinal disturbances. Others have been found to react with sunlight, and through a process known as photolysis, form even more toxic compounds. Farmers facing standing cornfields should know their risks. With results such as this in test animals, it would certainly be worthwhile to investigate the incidence of these conditions among people living in close proximity to agricultural areas. WebI have friends who used to live in a farmhouse surrounded by cornfields, with a very long driveway. 4. According to researchers Devesa and Fears at the the National Cancer Institute in Bethesda, Maryland, the incidence rates for NHL have increased at about 3-4% per year (Cancer Research, 1;52(Suppl 19):5432s-5440s, October, 1992). Also, critics of this study (such as those funded by agricultural interests) do not take into account that EPA guidelines on pesticide safety consider only at one pesticide at a time, however, children (and all of us) are exposed to many pesticides in food simulneously. For example, if pesticide levels were the same in both groups, it suggests that pesticides do not harm the body in a way that increases diabetes. There was not any increased cancer risk when applicators were studied for only 5 years implying it takes over 5 years to accumulate enough damage to the genetic structure to develop the cancers. Read More. View Original Journal Article 3. This is the conclusion from the following report summarizing over 25 peer reviewed studies over the past 30 years. Median levels of 2,5-DCP in adults in a non-agricultural setting were 6.6 to 10/4 mcg/l (NHANES 2003-2008). Aarhus University, Aarhus, Denmark, Diabetes Linked to Higher Blood Pesticide Levels, SOURCE: Environmental Science and Pollution Research, 22(1):379-386, Jan 2015 But if you Unfortunately, the tight-junctions can become "lose" after exposure to some chemicals in the environment - thereby, allowing toxic chemicals into the brain cell network with potential for causing elevated damage to the brain. 1. This was one of several questions researchers at Mansoura University Childrens Hospital in Egypt wanted to answer. After 7 years - all mothers were contacted and their children tested for intellectual performance using the Wechsler Intelligence Scale for Children, 4th edition. When this occurs, elevated levels of poisons enter the brain resulting in accelerated decline of brain function. Autoantibodies were found toward smooth muscle, parietal cell, brush border, thyroid gland, myelin, and ANA. The purpose of the study was to determine how the pesticide combination affected the immune systems of two amphibian frog species. Continuous breathing of low levels of nerve poisons is suspected of accelerating the aging process by suppressing or damaging genes involved in maintaining health. We were able to demonstrate that an organic diet provides a dramatic and immediate protective effect against exposures to organophosphorus pesticides that are commonly used in agricultural production.The persistent existence of OP pesticide metabolites in urine during the conventional diet periods raises a concern of the possible chronic exposures to OP pesticides in children. Illnesses occurring at higher rates for people living close to agriculture include birth defects, brain cancer, autism, infertility, miscarriage, Parkinson's Disease, immune system damage, leukemia, developmental brain damage in children, higher rates of child cancers, non-Hodgkin's lymphoma, autoimmune disorders, arthritis, lupus and diabetes. View Original Journal Article It is important to remember, that pesticides are designed with the specific intent to damage biological processes within an organism, which is why even very low levels would be able to cause harm over time. Epilepsia, Volume 47(11):1761-1774, November, 2006 These allergens accumulate in the human body for years and negatively affect but diabetes children had levels of 0.20, 3. Wilms' tumor is a type of kidney cancer that is the fourth most common childhood cancer, accounting for approximately 6% of all malignancies diagnosed before 15 years of age). A. Aschengrau, D. Ozonoff, P.Coogan, R. Vezina, T. Heeren Other common pesticides (organophosphates and carbamates), raised the risk of miscarriage by 40%. This entire report has been translated to Spanish which can be viewed HERE. Conducted in part by the Centers for Disease Control, scientists studied the effects of eating organic (non-pesticide) food among 23 elementary school children ages 3 to 11. A type of kidney cancer known as Wilms' tumor occured nearly 60% higher than expected in children whose fathers worked around pesticides. While this report emphasizes the dangers of residential homes close to agriculture, similar health effects could be expected for those working in offices or schools within one mile from agriculture as well. Child exposure can occur from pesticides on the father being inhaled and transferred to the child. Results showed that families living within 1/4 mile from the orchards had house dust concentrations 7 times higher than found in the reference homes. Saudi Arabia has one of the highest rates of diabetes in the world. University of Washington, Seattle, Washington, Miscarriage Rates Higher Near Agriculture, SOURCE: Epidemiology, March 2001 Some pesticides react with sunlight (. When using these numbers to determine increased risk from the pesticides, the researchers found that children with high levels of malathion in their blood had a 4 times greater risk of developing diabetes than children with low levels of malathion. 390 neuroblastoma children and 460 non-cancer controls were included in the study. The results showed the children living in the pesticide treated homes had nearly 4 times greater risk of developing the disease. There are 550 new cases in the United States each year, with an annual incidence rate of 9.2 cases per million children under 15 years of age. Dr. Eric Richfield, a neurologist who worked on the study, said it may mean that no one will ever be able to predict who is at risk of Parkinson's based on exposure to chemicals. Dr. Machera did not state if these chemicals were used on residential lawns as an anti-fungal agent. The cause of these health problems is believed to result from low level pesticide vapors that are present in the air days and sometimes weeks after application on food crops. The study, which involved almost 700 women in 10 California counties, showed that pregnant mothers who lived near food crops where certain pesticides were sprayed faced significantly increased rates of miscarriage due to birth defects. Exposure to pesticides was based on concentrations in urine samples. University of North Carolina Living Dr. Christine G. Parks School of Public Health, University of California, Berkeley, CA, Autism and Developmental Delays Higher in Children 43 farmers who had been using pesticides for 15 years were studied to determine if immune system abnormalities could be identified (thereby, increasing risk for cancer and viral infections). Hemochromatosis from Low Level Pesticide Exposure, SOURCE: International Journal of Molecular Medicine, Vol. Components that are planted with the gene for corn cause allergies in humans. Investigators questioned both parents regarding use of pesticides in and around the home. This pesticide is used to kill broadleaf weeds and is used when growing alfalfa, barley, clover, flax, lespedeza, oats, grass, peas, rice, rye, sorghum, trefoil, triticale, and wheat. This included: Further support for these findings is shown by the fact that the risk of ASD increased with the pounds of pesticide used and decreased with distance from the treated fields. If pesticide exposure occurred between the 3rd and 8th week of pregnancy, there was a 40% increase in major birth defects ending in fetal death. Families living near farms could be in danger from the spraying of pesticides and other chemicals, an official inquiry has concluded. Of great concern, health effects were seen not just for those just living directly next to the fields, but some studies showed effects up to 1 mile away! Chem-Tox Comment: While the pesticide chlorpyrifos was banned for indoor use in 2000 (under the name Dursban), it is still used in agriculture under the name Lorsban. It is also used on sod farm turf, golf courses, public walkways, pastures, rangelands and residential lawns. WebThe other downside to living near farms is the dust coming thru your screens, spring and fall, and I have never had a courtesy call to let me know they are coming to work the The following research was conducted at the Department of Pharmacology, Duke University Medical Center, Durham, North Carolina. Department of Neurology, University of California, Los Angeles, CA, Children Living Near Farms have Higher Levels of Pesticides View Journal Article The subjects were found to have an elevated number of CD26 cells and a higher rate of autoimmune problems, compared with two other control groups. The incidence rate of NHL has been rising 3-4% a year. In a related study described below, researchers found that switching to organic food resulted in a dramatic drop in malathion levels in children. Infant deaths for male babies (from congenital anomalies related to the birth defects) was over 2.5 times higher than normal. 2. During phase 2 (days 6 to 10) - children ate only organic foods. After many decades of being pointed to as a source of environmental issues, field crop agriculture is being looked to as one of the solutions to global climate change. Rashes. A combination of two commonly used agricultural pesticides, are showing the ability to cause the same pattern of brain damage seen in Parkinson's disease. This has enormous implications," Cory-Slechta said in a statement. (These rates were reported in the book "Principles and Practice of Pediatric Oncology, Lippincott-Raven, 1997). In research to determine the amount of air contamination following application of pesticides, it was found that the levels of the pesticide Dursban drop to one-sixth of its original 1 hour level four days after application. Men who mixed or applied the weed killer 2,4-D experienced a 50% higher rate of the cancer known as Non-Hodgkin's Lymphoma (also called NHL). The study on the effects of cyproconazole (lets call it CPZ for simplicity) was headed by Dr. K. Machera, at the Laboratory of Pesticide Toxicology in Athens, Greece. That leads many to question its safety. Along with use in agriculture, these chemicals are the used in school pest control - home pest control and community mosquito control applications from trucks and planes. In phase 3 (days 11 to 15), all children switched back to eating conventional foods grown with pesticides. Department of Epidemiology Of significant concern, it has been shown that children experience greater harm from pesticides because of their size and less efficient detoxification pathways. Read More. It could errupt at any time! Its major role is to keep toxic molecules out of the brain cell network. So creepy. Everyone is protected from pesticide harm by a liver enzyme known as cytochrome P-450. Riyadh, Saudi Arabia, Farmers have Increased Immune System Abnormalities, SOURCE: Ecotoxicology Environmental Safety Read More. Rates of diabetes and pre-diabetes were found to be 11 times higher in 116 men employed as pesticide sprayers from public mosquito vector control programs in Bolivia. View Original Journal Article The fetal body weight was significantly less even at the lowest dose of 20 mg/kg. Read More. 1. View Original Journal Article In this 1999 research, scientists exposed 10 day old rat pups to three separate pesticides. Dr. Machera exposed 10 pregnant animals to different levels of CPZ ranging from 20-75 mg/kg from the 6th to the 16th day of pregnancy. Lupus is an autoimmune disease in which the body's immune system mistakenly attacks a person's healthy tissue including the heart, lungs and brain. Read More. View Original Journal Article Looking at pesticide use for the lawn and garden resulted in an increased risk of 120% (Odds Ratio=2.2) when the mother had applied pesticides in the yard and 50% higher (Odds Ratio=1.5) when the father had applied pesticides in the yard. While this report emphasizes the dangers of residential homes close to agriculture, similar health effects could be expected for those working in offices or schools within one mile from agriculture as well. For more information on brain cancer and neuroblastoma see: For example, men who were exposed to the weed killer 20 or more days per year had over a 3 times greater chance of developing the disease. Chemicals now being found to damage the blood brain barrier take on new interest as research over the past decade has found defects in blood brain barrier function in people with Psychosis (1), Epilepsy (2), Alzheimers (3) and Parkinson's Disease (4). Along with this, farmers also had lower levels of regulatory B-cells that function to suppress overactive immunity (needed to suppress autoimmune conditions). Levels of the pesticide in pregnant women living in an agricultural region of Califoria had median urinary levels 2 to 3 times higher at 21.5 and 18.5 micrograms/liter (mcg/l) and 95th percentile values of approximately 1950 mcg/l (Castorina et al., 2010). (Metabolites occur after the original pesticide is processed by the liver). The study, published in July's 1987 issue of the Journal of the National Cancer Institute, studied 123 Los Angeles children with leukemia and 123 children without the malignancy. Although the research described here is not directly linked to living near agriculture, it does show how common pesticides can cause microcephaly. In a highly-critical report, the Royal "This is the first study to our knowledge of pesticides and pregnancy in which exposures were in close proximity to the subjects and the verification of pesticide use was objective, not relying on people's memories of what they might have been exposed to," Hertz-Picciotto said. Read More. 34(8), Nov 2014, http://www.ncbi.nlm.nih.gov/pubmed/25176568, http://www.spandidos-publications.com/ijmm/34/5/1395. Thus, chlorpyrifos (Lorsban), as used in pesticide spray, should be examined more closely as a probable immunotoxin. View Original Journal Article glyphosate, Obesity Higher in Children with Higher Pesticide Levels, SOURCE: Reviews of Environmental Health, 26(3): 215-9, 2011 Researchers also stated CD4 T and B cells that process antigens are possibly undergoing proliferative exhaustion. 2. Research Center for Eco-Environmental Sciences Does eating chemically grown commercial food increase the rate of diabetes in children? Prickling and/or burning skin. 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